| Long name: |
ATXN1 (Ser775) Primary Polyclonal Antibody |
| Also known as: |
ATXN1 (Ser775) PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
ATXN1 Ser775 |
| Specificity: |
This is a highly specific antibody against ATXN1 Ser775 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Ser775 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human Ataxin-1 around the phosphorylation site of Ser775 |
| Gene ID number: |
6310 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
2, 3, 4 and 6, ADCA has been divided into three groups: ADCA types I-III, ADCA is caused by the expansion of the CAG repeats, ADCAI is genetically heterogeneous, ADCAII, At least two transcript variants encoding the same protein have been found for this gene, Clinically, Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions, The expanded repeats are variable in size and unstable, The function of the ataxins is not known, This locus has been mapped to chromosome 6, [provided by RefSeq], and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), and is associated with spinocerebellar ataxia type 1 (SCA1), and it has been determined that the diseased allele contains41-81 CAG repeats, are most likely homogeneous disorders, being assigned to five different chromosomes, brain stem and spinal cord, compared to 6-39 in the normal allele, designated spinocerebellar ataxia (SCA) 1, producing an elongated polyglutamine tract in the corresponding protein, usually increasing in size when transmitted to successive generations, which always presents with retinal degeneration (SCA7), with five genetic loci, The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
ATX1, ATX1_HUMAN, Ataxin-1, D6S504E, SCA1, Spinocerebellar ataxia type 1, ATXN1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ATXN1 (Ser775) |
| Short name: |
ATXN1 (Ser775) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ATXN1 (Ser775) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10548 |
| Gene: |
ATXN1 |
More about : ATXN1 |
| Long gene name: |
ataxin 1 |
| Synonyms gene: |
SCA1 |
| Synonyms gene name: |
ataxin 1) , autosomal dominant, spinocerebellar ataxia 1 (olivopontocerebellar ataxia 1 |
| Synonyms: |
D6S504E ATX1 |
| Locus: |
6p22, 3 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
X79204 |
| Entrez gene record: |
6310 |
| Pubmed identfication: |
1582256 |
| RefSeq identity: |
NM_000332 |
| Classification: |
Ataxins |
| Havana BLAST/BLAT: |
OTTHUMG00000014303 |
| Locus Specific Databases: |
LRG_863 |