| Catalog number: | bs-4027R-A488 |
|---|---|
| Price: | 558 € |
| Supplier: | acr |
| Product name: | PFKL (Ser775) Antibody, ALEXA FLUOR 488 |
| Quantity: | 0,1 mg |
| Related search: |
| Long name: | ALEXA FLUOR 488 Conjugated, PFKL (Ser775) Polyclonal Antibody |
|---|---|
| Also known as: | Anti-PFKL Ser775 PAb ALEXA FLUOR 488 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 488, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | PFKL Ser775 |
| Specificity: | This is a highly specific antibody against PFKL Ser775 |
| Modification: | Phosphorylation |
| Modification Site: | Ser775 |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | KLH conjugated synthetic phosphopeptide derived from human PFKL around the phosphorylation site of Ser775 |
| Gene ID Number: | 5211 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | Mammalian PFK is a tetramer made up of diverse combinations of three isoenzymes: muscle (PFK-1), Overexpression of PFKL in transgenic mice results in a diminished glucose-induced insulin response, PFKL (phosphofructokinase, PFKL is expressed at high levels in Down's syndrome (DS) patients, also referred to as PFK-B (Phosphofructo-1-kinase isozyme B), liver (PFKL) and platelet (PFKP), liver), phosphofructokinase 1 or phosphohexokinase, predominates in organs with active gluconeogenesis, such as liver and kidney, suggesting a possible role for PFKL in the pathogenesis of DS, which suggests that PFKL may play a role in glucose-induced insulin secretion, 6-bisphosphate, Phosphofructokinases (PFKs) are regulatory glycolytic enzymes that catalyze the irreversible conversion of fructose-6-phosphate to fructose-1 |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 499nm/519nm |
| Properties: | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the PFKL (Ser775) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | Alexa Fluor |
| Gene target: | PFKL (Ser775) |
| Short name: | PFKL (Ser775) Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Label: | ALEXA FLUOR 488 |
| Alternative name: | ALEXA FLUOR 488, PFKL (Ser775) (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 8876 |
| Gene: | PFKL | More about : PFKL |
| Long gene name: | liver type , phosphofructokinase |
| Locus: | 21q22, 3 |
| Discovery year: | 1986-01-01 |
| Entrez gene record: | 5211 |
| Havana BLAST/BLAT: | OTTHUMG00000086910 |
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