ATXN1 (Ser775) Antibody, ALEXA FLUOR 488

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Catalog number: bs-3008R-A488
Price: 453 €
Supplier: MBS Polyclonals
Product name: ATXN1 (Ser775) Antibody, ALEXA FLUOR 488
Quantity: 100ug
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Long name: ALEXA FLUOR 488 Conjugated, ATXN1 (Ser775) Polyclonal Antibody
Also known as: Anti-ATXN1 Ser775 PAb ALEXA FLUOR 488
Category: Conjugated Primary Antibodies
Conjugated with: 488, ALEXA FLUOR®
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: ATXN1 Ser775
Specificity: This is a highly specific antibody against ATXN1 Ser775
Modification: Phosphorylation
Modification Site: Ser775
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Source: KLH conjugated synthetic phosphopeptide derived from human Ataxin-1 around the phosphorylation site of Ser775
Gene ID Number: 6310
Tested applications: IF(IHC-P)
Recommended dilutions: IF(IHC-P)(1:50-200)
Crossreactivity: Mouse, Rat, Human
Cross-reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen: 2, 3, 4 and 6, ADCA has been divided into three groups: ADCA types I-III, ADCA is caused by the expansion of the CAG repeats, ADCAI is genetically heterogeneous, ADCAII, At least two transcript variants encoding the same protein have been found for this gene, Clinically, Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions, The expanded repeats are variable in size and unstable, The function of the ataxins is not known, This locus has been mapped to chromosome 6, [provided by RefSeq], and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), and is associated with spinocerebellar ataxia type 1 (SCA1), and it has been determined that the diseased allele contains41-81 CAG repeats, are most likely homogeneous disorders, being assigned to five different chromosomes, brain stem and spinal cord, compared to 6-39 in the normal allele, designated spinocerebellar ataxia (SCA) 1, producing an elongated polyglutamine tract in the corresponding protein, usually increasing in size when transmitted to successive generations, which always presents with retinal degeneration (SCA7), with five genetic loci, The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum
Purification: Purified by Protein A
Storage conditions: 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission: 499nm/519nm
Synonyms: D6S504E ATX1
Properties: ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the ATXN1 (Ser775) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation: Alexa Fluor
Gene target: ATXN1 (Ser775)
Short name: ATXN1 (Ser775) Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Label: ALEXA FLUOR 488
Alternative name: ALEXA FLUOR 488, ATXN1 (Ser775) (Antibody to)
Alternative technique: antibodies
Identity: 10548
Gene: ATXN1 | More about : ATXN1
Long gene name: ataxin 1
Synonyms gene: SCA1
Synonyms gene name: ataxin 1) , autosomal dominant, spinocerebellar ataxia 1 (olivopontocerebellar ataxia 1
Locus: 6p22, 3
Discovery year: 1986-01-01
GenBank acession: X79204
Entrez gene record: 6310
Pubmed identfication: 1582256
RefSeq identity: NM_000332
Classification: Ataxins
Havana BLAST/BLAT: OTTHUMG00000014303
Locus Specific Databases: LRG_863

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