| Long name: |
Cy3 Conjugated, Adenomatous Polyposis Coli Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
APC/Adenomatous Polyposis Coli |
| Specificity: |
This is a highly specific antibody against APC/Adenomatous Polyposis Coli |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
2790-2843/2843 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human APC |
| Gene ID number: |
324 |
| Swiss Prot: |
P25054 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
APC activity is correlated with its phosphorylation state, Activates the GEF activity of SPATA13 and ARHGEF4, Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex, It is required for the localization of MACF1 to the cell membrane and this localization of MACF1 is critical for its function in microtubule stabilization, Plays a role in hepatocyte growth factor (HGF)-induced cell migration, Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator, Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells, Tumor suppressor |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Synonyms: |
APC, Adenomatous polyposis coli protein, BTPS2, DP2, DP2, DP3, Deleted in polyposis 2, PPP1R46, Protein APC, 5, 5, GS |
| Properties: |
1 of the Adenomatous Polyposis Coli Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Adenomatous Polyposis Coli Conjugated |
| Short name: |
Conjugated, Adenomatous Polyposis Coli Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, Adenomatous Polyposis Coli (Antibody to) |
| Alternative technique: |
antibodies |