| Long name: |
ALEXA FLUOR 488 Conjugated, Adenomatous Polyposis Coli Antibody |
| Also known as: |
Anti-APC/Adenomatous Polyposis Coli PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
APC/Adenomatous Polyposis Coli |
| Specificity: |
This is a highly specific antibody against APC/Adenomatous Polyposis Coli |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
2790-2843/2843 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human APC |
| Gene ID Number: |
324 |
| Swiss Prot: |
P25054 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
APC activity is correlated with its phosphorylation state, Activates the GEF activity of SPATA13 and ARHGEF4, Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex, It is required for the localization of MACF1 to the cell membrane and this localization of MACF1 is critical for its function in microtubule stabilization, Plays a role in hepatocyte growth factor (HGF)-induced cell migration, Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator, Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells, Tumor suppressor |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
APCL |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Adenomatous Polyposis Coli Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Adenomatous Polyposis Coli |
| Short name: |
Adenomatous Polyposis Coli Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, Adenomatous Polyposis Coli (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
24036 |
| Gene: |
APC2 |
More about : APC2 |
| Long gene name: |
APC2, WNT signaling pathway regulator |
| Synonyms gene name: |
adenomatosis polyposis coli 2 |
| Synonyms name: |
adenomatous polyposis coli like |
| Locus: |
19p13, 3 |
| Discovery year: |
2004-03-18 |
| Entrez gene record: |
10297 |
| Pubmed identfication: |
9823329 10021369 |
| RefSeq identity: |
NM_005883 |
| Classification: |
Armadillo repeat containing |
| Havana BLAST/BLAT: |
OTTHUMG00000180059 |