| Long name: |
ALEXA FLUOR 647 Conjugated, PKC gamma/SCA14 Polyclonal Antibody |
| Also known as: |
Anti-PKC gamma/SCA14 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PKC gamma/SCA14 |
| Specificity: |
This is a highly specific antibody against PKC gamma/SCA14 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PKC gamma/SCA14 |
| Gene ID Number: |
5582 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14), Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells, It has been demonstrated that several neuronal functions, Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development, PKC also serve as major receptors for phorbol esters, PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways, PKC gamma is expressed solely in the brain and spinal cord and its localization is restricted to neurons, The protein encoded by this gene is one of the PKC family members, There have been at least 12 different PKC isoforms identified in humans to date including alpha, a class of tumor promoters, and mu, beta I, beta II, delta, epsilon, eta, gamma, including long term potentiation (LTP) and long term depression (LTD), iota, lambda, specifically require this kinase, theta, zeta, Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
PKCC MGC57564 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the PKC gamma/SCA14 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
PKC gamma/SCA14 |
| Short name: |
PKC gamma/SCA14 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, PKC g/SCA14 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9402 |
| Gene: |
PRKCG |
More about : PRKCG |
| Long gene name: |
protein kinase C gamma |
| Synonyms gene: |
PKCG SCA14 |
| Synonyms gene name: |
gamma , protein kinase C |
| Synonyms name: |
PKC-gamma |
| Locus: |
19q13, 42 |
| Discovery year: |
1991-08-02 |
| GenBank acession: |
M13977 |
| Entrez gene record: |
5582 |
| Pubmed identfication: |
8432525 3755548 |
| RefSeq identity: |
NM_002739 |
| Classification: |
C2 domain containing protein kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000064846 |
| Locus Specific Databases: |
LRG_669 , Mutations of the Protein Kinase C &, #947 |