| Long name: |
Cy5, 5 Conjugated, PKC gamma/SCA14 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PKC gamma/SCA14 |
| Specificity: |
This is a highly specific antibody against PKC gamma/SCA14 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human PKC gamma/SCA14 |
| Gene ID number: |
5582 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14), Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells, It has been demonstrated that several neuronal functions, Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development, PKC also serve as major receptors for phorbol esters, PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways, PKC gamma is expressed solely in the brain and spinal cord and its localization is restricted to neurons, The protein encoded by this gene is one of the PKC family members, There have been at least 12 different PKC isoforms identified in humans to date including alpha, a class of tumor promoters, and mu, beta I, beta II, delta, epsilon, eta, gamma, including long term potentiation (LTP) and long term depression (LTD), iota, lambda, specifically require this kinase, theta, zeta, Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
PKCC MGC57564 |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
PKC gamma/SCA14 Conjugated |
| Short name: |
Conjugated, PKC gamma/SCA14 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 5 coupled, PKC g/SCA14 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9402 |
| Gene: |
PRKCG |
More about : PRKCG |
| Long gene name: |
protein kinase C gamma |
| Synonyms gene: |
PKCG SCA14 |
| Synonyms gene name: |
gamma , protein kinase C |
| Synonyms name: |
PKC-gamma |
| Locus: |
19q13, 42 |
| Discovery year: |
1991-08-02 |
| GenBank acession: |
M13977 |
| Entrez gene record: |
5582 |
| Pubmed identfication: |
8432525 3755548 |
| RefSeq identity: |
NM_002739 |
| Classification: |
C2 domain containing protein kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000064846 |
| Locus Specific Databases: |
LRG_669 , Mutations of the Protein Kinase C &, #947 |