| Long name: |
ATG1/ULK1 Primary Polyclonal Antibody |
| Also known as: |
ATG1/ULK1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
ATG1/ULK1 |
| Specificity: |
This is a highly specific antibody against ATG1/ULK1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
1004-1050/1050 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ATG1/ULK1 |
| Gene ID number: |
8408 |
| Swiss Prot: |
O75385 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Activated via phosphorylation by AMPK and also acts as a regulator of AMPK by mediating phosphorylation of AMPK subunits PRKAA1, Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, May phosphorylate ATG13/KIAA652 and RPTOR, PRKAB2 and PRKAG1, Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR, Plays a role early in neuronal differentiation and is required for granule cell axon formation, however such data need additional evidences, leading to negatively regulate AMPK activity, the precursors of autophagosomes, Serine/threonine-protein kinase involved in autophagy in response to starvation |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
ATG1A, Autophagy-related protein 1 homolog, KIAA722, Serine/threonine-protein kinase ULK1, ULK1, UNC51, Unc-51-like kinase 1, Unc51, hATG1, 1, ATG1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ATG1/ULK1 |
| Short name: |
ATG1/ULK1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ATG1/ULK1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12558 |
| Gene: |
ULK1 |
More about : ULK1 |
| Long gene name: |
unc-51 like autophagy activating kinase 1 |
| Synonyms gene name: |
elegans) , elegans)-like kinase 1 unc-51-like kinase 1 (C, unc-51 (C |
| Synonyms: |
ATG1 ATG1A |
| Synonyms name: |
ATG1 autophagy related 1 homolog (S, cerevisiae) |
| Locus: |
12q24, 33 |
| Discovery year: |
1998-09-03 |
| GenBank acession: |
AF045458 |
| Entrez gene record: |
8408 |
| Pubmed identfication: |
9693035 |
| Classification: |
Autophagy related |
| Havana BLAST/BLAT: |
OTTHUMG00000168052 |