| Long name: |
Cy3 Conjugated, ATG1/ULK1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ATG1/ULK1 |
| Specificity: |
This is a highly specific antibody against ATG1/ULK1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
1004-1050/1050 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human ATG1/ULK1 |
| Gene ID number: |
8408 |
| Swiss Prot: |
O75385 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Activated via phosphorylation by AMPK and also acts as a regulator of AMPK by mediating phosphorylation of AMPK subunits PRKAA1, Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, May phosphorylate ATG13/KIAA652 and RPTOR, PRKAB2 and PRKAG1, Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR, Plays a role early in neuronal differentiation and is required for granule cell axon formation, however such data need additional evidences, leading to negatively regulate AMPK activity, the precursors of autophagosomes, Serine/threonine-protein kinase involved in autophagy in response to starvation |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Synonyms: |
ATG1 ATG1A |
| Properties: |
1 of the ATG1/ULK1 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ATG1/ULK1 Conjugated |
| Short name: |
Conjugated, ATG1/ULK1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, ATG1/ULK1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12558 |
| Gene: |
ULK1 |
More about : ULK1 |
| Long gene name: |
unc-51 like autophagy activating kinase 1 |
| Synonyms gene name: |
elegans) , elegans)-like kinase 1 unc-51-like kinase 1 (C, unc-51 (C |
| Synonyms name: |
ATG1 autophagy related 1 homolog (S, cerevisiae) |
| Locus: |
12q24, 33 |
| Discovery year: |
1998-09-03 |
| GenBank acession: |
AF045458 |
| Entrez gene record: |
8408 |
| Pubmed identfication: |
9693035 |
| Classification: |
Autophagy related |
| Havana BLAST/BLAT: |
OTTHUMG00000168052 |