| Long name: |
FITC Conjugated, ADAMTS5 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ADAMTS5 |
| Specificity: |
This is a highly specific antibody against ADAMTS5 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
530-580/930 |
| Subcellular location: |
Secreted |
| Source: |
KLH conjugated synthetic peptide derived from human ADAMTS5 |
| Gene ID number: |
11096 |
| Swiss Prot: |
Q9UNA0 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
May play a role in proteolytic processing mostly during the peri-implantation period, May play an important role in the destruction of aggrecan in arthritic diseases, a cartilage proteoglycan, and may be involved in its turnover, Cleaves aggrecan |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
ADMP-2 ADAMTS11 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ADAMTS5 Conjugated |
| Short name: |
FITC Conjugated, ADAMTS5 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
5 (Antibody to), fluorecein coupled, ADAM metallopeptidase including thrombospondin classification 1 motif |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
5, ADAM-TS 11 and ADAM-TS 5 and ADAM-TS5 and ADAMTS-11 and ADAMTS-5 and ADAMTS11 and ADMP-2, ADAMTS5 and IDBG-1207 and ENSG00000154736 and 11096, ADAMTS5 and IDBG-630284 and ENSBTAG00000000648 and 286805, Adamts5 and IDBG-173252 and ENSMUSG00000022894 and 23794, Extracellular, this GO :0004222 and metalloendopeptidase activity and molecular function this GO :0005178 and integrin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0006508 and proteolysis and biological process this GO :0008237 and metallopeptidase activity and molecular function this GO :0008270 and zinc ion binding and molecular function this GO :0022617 and extracellular matrix disassembly and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0031012 and extracellular matrix and cellular component this GO :0042742 and defense response to bacterium and biological process, this GO :0004222 : metalloendopeptidase activity, this GO :0004222 : metalloendopeptidase activity and also this GO :0005178 : integrin binding and also this GO :0005515 : protein binding and also this GO :0008237 : metallopeptidase activity and also this GO :0008270 : zinc ion binding, this GO :0005178 : integrin binding, this GO :0005515 : protein binding, this GO :0008237 : metallopeptidase activity, this GO :0008270 : zinc ion binding, zinc ion binding, ADAM metallopeptidase with thrombospondin type 1 motif |
| Identity: |
221 |
| Gene: |
ADAMTS5 |
More about : ADAMTS5 |
| Long gene name: |
ADAM metallopeptidase with thrombospondin type 1 motif 5 |
| Synonyms gene name: |
5 (aggrecanase-2) , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif |
| Synonyms name: |
aggrecanase-2 |
| Locus: |
21q21, 3 |
| Discovery year: |
1999-08-23 |
| GenBank acession: |
AF142099 |
| Entrez gene record: |
11096 |
| Pubmed identfication: |
10438522 |
| Classification: |
ADAM metallopeptidases with thrombospondin type 1 motif |
| Havana BLAST/BLAT: |
OTTHUMG00000078686 |