| Long name: |
ADAMTS5 Primary Polyclonal Antibody |
| Also known as: |
ADAMTS5 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
ADAMTS5 |
| Specificity: |
This is a highly specific antibody against ADAMTS5 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
530-580/930 |
| Subcellular location: |
Secreted |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ADAMTS5 |
| Gene ID number: |
11096 |
| Swiss Prot: |
Q9UNA0 |
| Tested Applications: |
IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
May play a role in proteolytic processing mostly during the peri-implantation period, May play an important role in the destruction of aggrecan in arthritic diseases, a cartilage proteoglycan, and may be involved in its turnover, Cleaves aggrecan |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
A disintegrin and metalloproteinase with thrombospondin motifs 11, A disintegrin and metalloproteinase with thrombospondin motifs 5, ADAM-TS 11, ADAM-TS 5, ADAM-TS5, ADAMTS-11, ADAMTS-5, ADAMTS11, ADAMTS5, ADMP2, Aggrecanase-2, ADMP-2 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ADAMTS5 |
| Short name: |
ADAMTS5 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
5 (Antibody to), ADAM metallopeptidase including thrombospondin classification 1 motif |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
5, ADAM-TS 11 and ADAM-TS 5 and ADAM-TS5 and ADAMTS-11 and ADAMTS-5 and ADAMTS11 and ADMP-2, ADAMTS5 and IDBG-1207 and ENSG00000154736 and 11096, ADAMTS5 and IDBG-630284 and ENSBTAG00000000648 and 286805, Adamts5 and IDBG-173252 and ENSMUSG00000022894 and 23794, Extracellular, this GO :0004222 and metalloendopeptidase activity and molecular function this GO :0005178 and integrin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0006508 and proteolysis and biological process this GO :0008237 and metallopeptidase activity and molecular function this GO :0008270 and zinc ion binding and molecular function this GO :0022617 and extracellular matrix disassembly and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0031012 and extracellular matrix and cellular component this GO :0042742 and defense response to bacterium and biological process, this GO :0004222 : metalloendopeptidase activity, this GO :0004222 : metalloendopeptidase activity and also this GO :0005178 : integrin binding and also this GO :0005515 : protein binding and also this GO :0008237 : metallopeptidase activity and also this GO :0008270 : zinc ion binding, this GO :0005178 : integrin binding, this GO :0005515 : protein binding, this GO :0008237 : metallopeptidase activity, this GO :0008270 : zinc ion binding, zinc ion binding, ADAM metallopeptidase with thrombospondin type 1 motif |
| Identity: |
221 |
| Gene: |
ADAMTS5 |
More about : ADAMTS5 |
| Long gene name: |
ADAM metallopeptidase with thrombospondin type 1 motif 5 |
| Synonyms gene name: |
5 (aggrecanase-2) , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif |
| Synonyms: |
ADMP-2 ADAMTS11 |
| Synonyms name: |
aggrecanase-2 |
| Locus: |
21q21, 3 |
| Discovery year: |
1999-08-23 |
| GenBank acession: |
AF142099 |
| Entrez gene record: |
11096 |
| Pubmed identfication: |
10438522 |
| Classification: |
ADAM metallopeptidases with thrombospondin type 1 motif |
| Havana BLAST/BLAT: |
OTTHUMG00000078686 |