| Long name: |
FITC Conjugated, SHIP1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SHIP1 |
| Specificity: |
This is a highly specific antibody against SHIP1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human SHIP1 |
| Gene ID number: |
3635 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
At the plasma membrane, Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation in response to multiple cytokine and B and T cell receptor activation, Overall the protein functions as a negative regulator of myeliod cell proliferation and survival, an inositol phosphatase domain, and two C-terminal protein interaction domains, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3, thereby affecting multiple signaling pathways, 3, 4, 4, 5)-trisphosphate and inositol-1, 5-tetrakisphosphate, SHIP1 is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and contains an N-terminal SH2 domain |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
SHIP hp51CN SHIP1 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SHIP1 Conjugated |
| Short name: |
FITC Conjugated, SHIP1 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, SHIP1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6079 |
| Gene: |
INPP5D |
More about : INPP5D |
| Long gene name: |
inositol polyphosphate-5-phosphatase D |
| Synonyms gene name: |
145kD inositol polyphosphate-5-phosphatase, 145kDa , inositol polyphosphate-5-phosphatase |
| Synonyms name: |
SH2 domain-containing inositol 5', -phosphatase 1 |
| Locus: |
2q37, 1 |
| Discovery year: |
1996-04-04 |
| GenBank acession: |
U57650 |
| Entrez gene record: |
3635 |
| Pubmed identfication: |
8643691 8874179 |
| RefSeq identity: |
NM_001017915 |
| Classification: |
Phosphoinositide phosphatases SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000133688 |