| Long name: |
Cy5, 5 Conjugated, SHIP1 (Tyr1020) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SHIP1 Tyr1020 |
| Specificity: |
This is a highly specific antibody against SHIP1 Tyr1020 |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr1020 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human SHIP1 around the phosphorylation site of Tyr1020 |
| Gene ID number: |
3635 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
At the plasma membrane, Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation in response to multiple cytokine and B and T cell receptor activation, Overall the protein functions as a negative regulator of myeliod cell proliferation and survival, an inositol phosphatase domain, and two C-terminal protein interaction domains, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3, thereby affecting multiple signaling pathways, 3, 4, 4, 5)-trisphosphate and inositol-1, 5-tetrakisphosphate, SHIP1 is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and contains an N-terminal SH2 domain |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
SHIP hp51CN SHIP1 |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
SHIP1 (Tyr1020) Conjugated |
| Short name: |
Conjugated, SHIP1 (Tyr1020) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 5 coupled, SHIP1 (Tyr1020) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6079 |
| Gene: |
INPP5D |
More about : INPP5D |
| Long gene name: |
inositol polyphosphate-5-phosphatase D |
| Synonyms gene name: |
145kD inositol polyphosphate-5-phosphatase, 145kDa , inositol polyphosphate-5-phosphatase |
| Synonyms name: |
SH2 domain-containing inositol 5', -phosphatase 1 |
| Locus: |
2q37, 1 |
| Discovery year: |
1996-04-04 |
| GenBank acession: |
U57650 |
| Entrez gene record: |
3635 |
| Pubmed identfication: |
8643691 8874179 |
| RefSeq identity: |
NM_001017915 |
| Classification: |
Phosphoinositide phosphatases SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000133688 |