| Long name: |
SHIP1 Primary Polyclonal Antibody |
| Also known as: |
SHIP1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
SHIP1 |
| Specificity: |
This is a highly specific antibody against SHIP1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SHIP1 |
| Gene ID number: |
3635 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
At the plasma membrane, Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation in response to multiple cytokine and B and T cell receptor activation, Overall the protein functions as a negative regulator of myeliod cell proliferation and survival, an inositol phosphatase domain, and two C-terminal protein interaction domains, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3, thereby affecting multiple signaling pathways, 3, 4, 4, 5)-trisphosphate and inositol-1, 5-tetrakisphosphate, SHIP1 is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and contains an N-terminal SH2 domain |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
5-trisphosphate 5-phosphatase 1, INPP 5D, INPP5D, INPP5D protein, Inositol polyphosphate 5 phosphatase, Inositol polyphosphate 5 phosphatase 145kDa, Inositol polyphosphate 5 phosphatase D, Inositol polyphosphate-5-phosphatase of 145 kDa, MGC104855, MGC142140, MGC142142, Phosphatidylinositol 3, Phosphatidylinositol-3, SH2 containing inositol 5 phosphatase, SH2 containing inositol phosphatase isoform b, SH2 domain containing inositol 5' phosphatase 1, SH2 domain containing inositol phosphatase 1, SH2 domain-containing inositol phosphatase 1, SH2 domain-containing inositol-5''-phosphatase 1, SHIP 1, SHIP-1, SHIP1, SHIP1_HUMAN, SIP 145, SIP-145, SIP145, Signaling inositol polyphosphate 5 phosphatase SIP 145, Signaling inositol polyphosphate 5 phosphatase SIP145, hSHIP, hp51CN, p150 ship, p150Ship, 4, 4, 5 trisphosphate 5 phosphatase 1, Inositol polyphosphate 5 phosphatase of 145kDa |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SHIP1 |
| Short name: |
SHIP1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
SHIP1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6079 |
| Gene: |
INPP5D |
More about : INPP5D |
| Long gene name: |
inositol polyphosphate-5-phosphatase D |
| Synonyms gene name: |
145kD inositol polyphosphate-5-phosphatase, 145kDa , inositol polyphosphate-5-phosphatase |
| Synonyms: |
SHIP hp51CN SHIP1 |
| Synonyms name: |
SH2 domain-containing inositol 5', -phosphatase 1 |
| Locus: |
2q37, 1 |
| Discovery year: |
1996-04-04 |
| GenBank acession: |
U57650 |
| Entrez gene record: |
3635 |
| Pubmed identfication: |
8643691 8874179 |
| RefSeq identity: |
NM_001017915 |
| Classification: |
Phosphoinositide phosphatases SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000133688 |