Pin1 Antibody, ALEXA FLUOR 350

Catalog number:	bs-3541R-A350 Buy Now
Price:	348 €
Supplier:	MBS Polyclonals
Product name:	Pin1 Antibody, ALEXA FLUOR 350
Quantity:	0.12 ml
Related search:	pin alexa antibody peptidylprolyl tau cistrans isomerase synonyms

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Long name:	ALEXA FLUOR 350 Conjugated, Pin1 Polyclonal Antibody
Also known as:	Anti-Pin1 PAb ALEXA FLUOR 350
Category:	Conjugated Primary Antibodies
Conjugated with:	350, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	Pin1
Specificity:	This is a highly specific antibody against Pin1
Modification:	Unmodified
Modification Site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Source:	This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Pin1
Gene ID Number:	5300
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Cross-reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen:	Peptidyl-prolyl isomerases (PPIase) facilitate the cis-trans interconversion of the peptidyl-prolyl bond thereby affecting protein folding, Pin1 binds to tau phosphorylated specifically on the Thr231-Pro site and induces conformational changes in tau, Pin1 could be pivotal for maintainance of normal neuronal function and preventing age-dependent neurodegeneration, Pin1 expression inversely correlates with the predicted neuronal vulnerability in normally aged brain and also with actual neurofibrillary degeneration in AD brain, Pin1 has been implicated in tau pathologies that underlie Alzheimer's Disease, Pin1 is a PPIase which specifically recognizes phosphorylated S/T-P bonds, Such conformational changes can directly restore the ability of phosphorylated Tau to bind microtubules and promote microtubule assembly and/or facilitate tau dephosphorylation, Pin1 is a Peptidyl-prolyl isomerases (PPIase)
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	343nm/442nm
Synonyms:	dod
Properties:	ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	ALEXA FLUOR 350, Alexa Fluor
Gene target:	Pin1
Short name:	Pin1 Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 350
Alternative name:	ALEXA FLUOR 350, NIMA-interacting 1 (Antibody to), peptidylprolyl cis/trans isomerase
Alternative technique:	antibodies
Identity:	8988
Gene:	PIN1 | More about : PIN1
Long gene name:	NIMA-interacting 1 , peptidylprolyl cis/trans isomerase
Synonyms gene name:	protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1
Locus:	19p13
Discovery year:	1996-12-16
Entrez gene record:	5300
Pubmed identfication:	8606777
Classification:	Parvulins
Havana BLAST/BLAT:	OTTHUMG00000180388
Locus Specific Databases:	LRG_847

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