| Long name: |
ALEXA FLUOR 647 Conjugated, Pin1 (Ser16) Polyclonal Antibody |
| Also known as: |
Anti-Pin1 Ser16 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Pin1 Ser16 |
| Specificity: |
This is a highly specific antibody against Pin1 Ser16 |
| Modification: |
Phosphorylation |
| Modification Site: |
Ser16 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
1-50/163 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human Pin1 around the phosphorylation site of Ser16 |
| Gene ID Number: |
5300 |
| Swiss Prot: |
Q13526 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Binds and targets PML and BCL6 for degradation in a phosphorylation-dependent manner, Can transactivate multiple oncogenes and induce centrosome amplification, Catalyzes pSer/Thr-Pro cis/trans isomerizations, Displays a preference for an acidic residue N-terminal to the isomerized proline bond, Down-regulates kinase activity of BTK, Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation, chromosome instability and cell transformation, Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
PIN1, PPIase Pin1, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, Peptidyl-prolyl cis-trans isomerase Pin1, Rotamase Pin1, UBL5, DOD |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Pin1 (Ser16) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
Pin1 (Ser16) |
| Short name: |
Pin1 (Ser16) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, NIMA-interacting 1 (Ser16) (Antibody to), peptidylprolyl cis/trans isomerase |
| Alternative technique: |
antibodies |