| Long name: |
Biotin Conjugated, Tuberin (Ser1387) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Tuberin Ser1387 |
| Specificity: |
This is a highly specific antibody against Tuberin Ser1387 |
| Modification: |
Phosphorylation |
| Modification site: |
Ser1387 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human Tuberin around the phosphorylation site of Ser1387 |
| Gene ID number: |
7249 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
At least three isoforms of Tuberin exist, Interaction between hamartin (TSC1) and tuberin may facilitate vesicular docking, It may function in vesicular transport, It specifically stimulates the intrinsic GTPase activity of the Ras related protein RAP1A and RAB5, Mutations in tuberin lead to constitutive activation of RAP1A in tumors, and may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors, is implicated as a tumor suppressor, or TSC2 (Tuberous sclerosis complex), suggesting a possible mechanism for its role in regulating cellular growth, Tuberin |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
LAM, OTTHUMP00000158940, OTTHUMP00000198394, OTTHUMP00000198395, P-TSC2 Ser1387, TSC2, TSC2_HUMAN, TSC4, Tuberin, Tuberin phospho Ser1387, Tuberous sclerosis 2, Tuberous sclerosis 2 protein, Tuberous sclerosis 2 protein homolog, p-Tuberin Ser1387, FLJ43106, TSC2 Ser1387, Tuberinphospho S1387 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Tuberin (Ser1387) Conjugated |
| Short name: |
Conjugated, Tuberin (Ser1387) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, Tuberin (Ser1387) (Antibody to) |
| Alternative technique: |
antibodies |