Rictor (Thr1135) Antibody, ALEXA FLUOR 350

Catalog number:	bs-3387R-A350 Buy Now
Price:	587 €
Supplier:	acr
Product name:	Rictor (Thr1135) Antibody, ALEXA FLUOR 350
Quantity:	0,4 ml
Related search:	thr mtorc antibody phosphorylation conjugated ser alternative

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Long name:	ALEXA FLUOR 350 Conjugated, Rictor (Thr1135) Polyclonal Antibody
Also known as:	Anti-Rictor Thr1135 PAb ALEXA FLUOR 350
Category:	Conjugated Primary Antibodies
Conjugated with:	350, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	Rictor Thr1135
Specificity:	This is a highly specific antibody against Rictor Thr1135
Modification:	Phosphorylation
Modification Site:	Thr1135
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen range:	1100-1150/1732
Subcellular location:	Cytoplasm
Source:	KLH conjugated synthetic phosphopeptide derived from human Rictor around the phosphorylation site of Thr1135
Gene ID Number:	253260
Swiss Prot:	Q6R327
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Human
Cross-reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen:	Plays an essential role in embryonic growth and development, but, in contrast to mTORC1, mTORC2 also modulates the phosphorylation of PRKCA on 'Ser-657', mTORC2 is activated by growth factors, mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, mTORC2 promotes the serum-induced formation of stress-fibers or F-actin, mTORC2 regulates the phosphorylation of SGK1 at 'Ser-422', mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors, seems to be nutrient-insensitive, which may facilitate the phosphorylation of the activation loop of AKT1 on 'Thr-308' by PDK1 which is a prerequisite for full activation, which regulates cell growth and survival in response to hormonal signals, Subunit of mTORC2
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	343nm/442nm
Synonyms:	AVO3, AVO3 homolog, KIAA1999, RICTOR, Rapamycin-insensitive companion of mTOR, hAVO3, PIA
Properties:	ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	ALEXA FLUOR 350, Alexa Fluor
Gene target:	Rictor (Thr1135)
Short name:	Rictor (Thr1135) Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 350
Alternative name:	ALEXA FLUOR 350, Rictor (Thr1135) (Antibody to)
Alternative technique:	antibodies

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