| Long name: |
ALEXA FLUOR 647 Conjugated, Rictor (Thr1135) Polyclonal Antibody |
| Also known as: |
Anti-Rictor Thr1135 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Rictor Thr1135 |
| Specificity: |
This is a highly specific antibody against Rictor Thr1135 |
| Modification: |
Phosphorylation |
| Modification Site: |
Thr1135 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
1100-1150/1732 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human Rictor around the phosphorylation site of Thr1135 |
| Gene ID Number: |
253260 |
| Swiss Prot: |
Q6R327 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Plays an essential role in embryonic growth and development, but, in contrast to mTORC1, mTORC2 also modulates the phosphorylation of PRKCA on 'Ser-657', mTORC2 is activated by growth factors, mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, mTORC2 promotes the serum-induced formation of stress-fibers or F-actin, mTORC2 regulates the phosphorylation of SGK1 at 'Ser-422', mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors, seems to be nutrient-insensitive, which may facilitate the phosphorylation of the activation loop of AKT1 on 'Thr-308' by PDK1 which is a prerequisite for full activation, which regulates cell growth and survival in response to hormonal signals, Subunit of mTORC2 |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
AVO3, AVO3 homolog, KIAA1999, RICTOR, Rapamycin-insensitive companion of mTOR, hAVO3, PIA |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Rictor (Thr1135) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
Rictor (Thr1135) |
| Short name: |
Rictor (Thr1135) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, Rictor (Thr1135) (Antibody to) |
| Alternative technique: |
antibodies |