| Long name: |
ALEXA FLUOR 488 Conjugated, Raptor (Ser792) Polyclonal Antibody |
| Also known as: |
Anti-Raptor Ser792 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Raptor Ser792 |
| Specificity: |
This is a highly specific antibody against Raptor Ser792 |
| Modification: |
Phosphorylation |
| Modification Site: |
Ser792 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from mouse Raptor around the phosphorylation site of Ser792 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Partial inhibition of raptor expression by RNA interference (RNAi) reduces mTOR-catalyzed 4EBP1 phosphorylation in vitro, RNAi of C, Rapamycin or amino acid withdrawal increases, Raptor is a 150 kDa mTOR binding protein that also binds 4EBP1 and p70alpha, The binding of Raptor to mTOR is necessary for the mTOR-catalyzed phosphorylation of 4EBP1 in vitro, Thus, and it strongly enhances the mTOR kinase activity toward p70alpha, elegans raptor yields an array of phenotypes that closely resemble those produced by inactivation of Ce-TOR, in part by regulating p70 S6 kinase alpha (p70alpha) and eukaryotic initiation factor 4E binding protein 1 (4EBP1), raptor is an essential scaffold for the mTOR-catalyzed phosphorylation of 4EBP1 and mediates TOR action in vivo, the recovery of 4EBP1 and raptor on 7-methyl-GTP Sepharose, whereas insulin strongly inhibits, mTOR controls cell growth |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
KIAA1303, P150 target of rapamycin TOR-scaffold protein, RPTOR_HUMAN, Raptor phospho Ser792, Regulatory Associated Protein of mTOR, Regulatory-associated protein of mTOR, p-Raptor Ser792, p150 target of rapamycin TOR scaffold protein containing WD repeats, p150 target of rapamycin TOR-scaffold protein, ARaptor phospho S792 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Raptor (Ser792) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Raptor (Ser792) |
| Short name: |
Raptor (Ser792) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, Raptor (Ser792) (Antibody to) |
| Alternative technique: |
antibodies |