| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Raptor Ser792 |
| Specificity: |
This antibody reacts specifically with Raptor (Ser792) |
| Modification: |
Phosphorylation |
| Modification site: |
Ser792 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from mouse Raptor around the phosphorylation site of Ser792 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Partial inhibition of raptor expression by RNA interference (RNAi) reduces mTOR-catalyzed 4EBP1 phosphorylation in vitro, RNAi of C, Rapamycin or amino acid withdrawal increases, Raptor is a 150 kDa mTOR binding protein that also binds 4EBP1 and p70alpha, The binding of Raptor to mTOR is necessary for the mTOR-catalyzed phosphorylation of 4EBP1 in vitro, Thus, and it strongly enhances the mTOR kinase activity toward p70alpha, elegans raptor yields an array of phenotypes that closely resemble those produced by inactivation of Ce-TOR, in part by regulating p70 S6 kinase alpha (p70alpha) and eukaryotic initiation factor 4E binding protein 1 (4EBP1), raptor is an essential scaffold for the mTOR-catalyzed phosphorylation of 4EBP1 and mediates TOR action in vivo, the recovery of 4EBP1 and raptor on 7-methyl-GTP Sepharose, whereas insulin strongly inhibits, mTOR controls cell growth |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
KIAA1303, P150 target of rapamycin TOR-scaffold protein, RPTOR_HUMAN, Raptor phospho Ser792, Regulatory Associated Protein of mTOR, Regulatory-associated protein of mTOR, p-Raptor Ser792, p150 target of rapamycin TOR scaffold protein containing WD repeats, p150 target of rapamycin TOR-scaffold protein, ARaptor phospho S792 |
| Also known as: |
Raptor (Ser792) Polyclonal Antibody |
| Other name: |
Anti-Raptor (Ser792) Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Raptor (Ser792) |
| Short name: |
Anti-Raptor (Ser792) (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Raptor (Ser792) (polyclonal) |
| Alternative technique: |
polyclonals |