| Long name: |
Biotin Conjugated, Pin1 (Ser16) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Pin1 Ser16 |
| Specificity: |
This phosphorylation site is homologous across the listed species, This is a highly specific antibody against Pin1 Ser16 |
| Modification: |
Phosphorylation |
| Modification site: |
Ser16 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
1-50/163 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human Pin1 around the phosphorylation site of Ser16 |
| Gene ID number: |
5300 |
| Swiss Prot: |
Q13526 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Binds and targets PML and BCL6 for degradation in a phosphorylation-dependent manner, Can transactivate multiple oncogenes and induce centrosome amplification, Catalyzes pSer/Thr-Pro cis/trans isomerizations, Displays a preference for an acidic residue N-terminal to the isomerized proline bond, Down-regulates kinase activity of BTK, Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation, chromosome instability and cell transformation, Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
PIN1, PPIase Pin1, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, Peptidyl-prolyl cis-trans isomerase Pin1, Rotamase Pin1, UBL5, DOD |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Pin1 (Ser16) Conjugated |
| Short name: |
Conjugated, Pin1 (Ser16) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
NIMA-interacting 1 (Ser16) (Antibody to), biotinilated coupled, peptidylprolyl cis/trans isomerase |
| Alternative technique: |
antibodies |