| Long name: |
PAR4 (Thr163) Primary Polyclonal Antibody |
| Also known as: |
PAR4 (Thr163) PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
PAR4 Thr163 |
| Specificity: |
This is a highly specific antibody against PAR4 Thr163 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Thr163 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human PAR4 around the phosphorylation site of Thr163 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
2001), 2001), 2006), However, Mice lacking PAR4 are protected from mesenteric arteriole thrombosis, PAR1 and PAR3 are activated by thrombin, PAR4 is expressed along with PAR1 on human platelets, The PAR family consists of 4 receptors, and PAR2 and PAR4 are activated by several serine proteases (Macfarlane et al, and each plays an important role in thrombin-induced platelet aggregation (Holinstat et al, and platelets from mice lacking PAR4 fail to aggregate in response to thrombin (Sambrano et al, indicating that PAR4 is a potential target for treatment of thrombosis in humans, platelets from mice express PAR4 but not PAR1, that are activated by proteolytic cleavage of the N-terminal domain of the receptor to reveal a tethered ligand, the proteinase-activated receptors (PARs), PAR4 is a member of a unique family of GPCRs |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
2310001G03Rik, PAWR, PRKC Apoptosis WT1 Regulator, PRKC apoptosis WT1 regulator protein, Par4 induced by effectors of apoptosis, Prostate apoptosis response 4 protein, Prostate apoptosis response protein 4, Prostate apoptosis response protein PAR 4, Proteinase-Activated Receptor 4, TRANSCRIPTIONAL REPRESSOR PAR4, Transcriptional repressor Par-4-like protein PAWR, WT1 Interacting Protein, protease-activated receptor 4, PAR 4 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PAR4 (Thr163) |
| Short name: |
PAR4 (Thr163) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
PAR4 (Thr163) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
29998 |
| Gene: |
PWAR4 |
More about : PWAR4 |
| Long gene name: |
Prader Willi/Angelman region RNA 4 |
| Synonyms: |
PAR4 PAR-4 |
| Locus: |
15q11, 2 |
| Discovery year: |
2013-06-14 |
| Entrez gene record: |
347745 |
| Pubmed identfication: |
11106375 7987392 |