| Long name: |
FITC Conjugated, PAR4 (Thr163) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PAR4 Thr163 |
| Specificity: |
This is a highly specific antibody against PAR4 Thr163 |
| Modification: |
Phosphorylation |
| Modification site: |
Thr163 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human PAR4 around the phosphorylation site of Thr163 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
2001), 2001), 2006), However, Mice lacking PAR4 are protected from mesenteric arteriole thrombosis, PAR1 and PAR3 are activated by thrombin, PAR4 is expressed along with PAR1 on human platelets, The PAR family consists of 4 receptors, and PAR2 and PAR4 are activated by several serine proteases (Macfarlane et al, and each plays an important role in thrombin-induced platelet aggregation (Holinstat et al, and platelets from mice lacking PAR4 fail to aggregate in response to thrombin (Sambrano et al, indicating that PAR4 is a potential target for treatment of thrombosis in humans, platelets from mice express PAR4 but not PAR1, that are activated by proteolytic cleavage of the N-terminal domain of the receptor to reveal a tethered ligand, the proteinase-activated receptors (PARs), PAR4 is a member of a unique family of GPCRs |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
PAR4 PAR-4 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PAR4 (Thr163) Conjugated |
| Short name: |
FITC Conjugated, PAR4 (Thr163) Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, PAR4 (Thr163) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
29998 |
| Gene: |
PWAR4 |
More about : PWAR4 |
| Long gene name: |
Prader Willi/Angelman region RNA 4 |
| Locus: |
15q11, 2 |
| Discovery year: |
2013-06-14 |
| Entrez gene record: |
347745 |
| Pubmed identfication: |
11106375 7987392 |