Histone H2A.X (Ser140) Antibody

Catalog number:	bs-3185R Buy Now
Price:	602 €
Supplier:	genways
Product name:	Histone H2A.X (Ser140) Antibody
Quantity:	1 vial
Related search:	histone antibody dna antibodies hax alternative more

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Long name:	Histone H2A, X (Ser140) Antibody
Also known as:	Histone H2A, X (Ser140) Antibody
Category:	Primary Antibodies
Conjugation:	Unconjugated
Target Antigen:	Histone H2A, X Ser140
Specificity:	This phosphorylation site is homologous to that of Ser140 in Mouse and Rat, This is a highly specific antibody against Histone H2A, X Ser140
Modification(s):	Phosphorylation
Modification site(s):	Ser140
Clonality:	Polyclonal antibody
Clone number:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen range:	100-142/143
Subcellular location:	Nucleus
Source:	KLH conjugated synthetic phosphopeptide derived from human Histone H2AX around the phosphorylation site of Ser140
Gene ID number:	3014
Swiss Prot:	P16104
Tested Applications:	IF(IHC-P), IHC-P
Recommended dilutions:	IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivity:	Mouse, Rat, Human
Cross reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen:	DNA accessibility is regulated via a complex set of post-translational modifications of histones, DNA repair, DNA replication and chromosomal stability, Histones thereby play a central role in transcription regulation, Nucleosomes wrap and compact DNA into chromatin, Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation, also called histone code, and nucleosome remodeling, limiting DNA accessibility to the cellular machineries which require DNA as a template, Variant histone H2A which replaces conventional H2A in a subset of nucleosomes
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names:	H2A, H2A/X, H2AFX, Histone H2A, Histone H2AX, H2AX, X, X
Properties:	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target:	Histone H2A, X (Ser140)
Short name:	Histone H2A, X (Ser140) Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Alternative name:	Histone H2A, X (Ser140) (Antibody to)
Alternative technique:	antibodies

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