Dab1 (Ser524) Antibody, Biotin Conjugated

Catalog number:	bs-3116R-Biotin Buy Now
Price:	Ask price €
Supplier:	genways bulk
Product name:	Dab1 (Ser524) Antibody, Biotin Conjugated
Quantity:	bulk
Related search:	dab antibody ser antibodies biotin disabled gene homolog drosophila

More details Need more?:

Long name:	Biotin Conjugated, Dab1 (Ser524) Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	Biotinylated
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	Dab1 Ser524
Specificity:	This is a highly specific antibody against Dab1 Ser524
Modification:	Phosphorylation
Modification site:	Ser524
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Source:	KLH conjugated synthetic phosphopeptide derived from human Dab1 around the phosphorylation site of Ser524
Gene ID number:	1600
Tested applications:	IHC-P, WB
Recommended dilutions:	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity:	Mouse, Rat, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	Dab1 also mediates activation of Akt (PKB) by reelin resulting in inhibition of glycogen synthase kinase 3 beta (GSK-3 beta) and decreased phosphorylation of the microtubule-associated protein, Dab1 contains a phosphotyrosine binding (PTB) domain in the amino terminus, Dab1 is an intracellular adapter protein that functions in downstream signaling events initiated by the secreted protein reelin, Dab1 serine 491 is phosphorylated in a Cdk5-dependent manner and regulates, Phenotypically, Reelin-induced signaling during neural cortex development, Src family kinase and c-Abl activities are themselves then stimulated by binding to tyrosine phosphorylated Dab1, Tau, Tyrosine phosphorylation of Dab1 is increased by reelin binding to the Very Low Density Lipoprotein Receptor (VLDLR) and Apolipoprotein E Receptor 2 (ApoER2) through stimulation of Src family kinases, and severe cerebellar hypoplasia, disruption of neuronal migration, likely indirectly, the mutation of this gene produces motor defects and ataxia, Disabled 1 (Dab1) is an 80 kDa protein that is encoded by the Disabled-1 gene locus which is mutated in scrambler and yotari mutant mice
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Synonyms:	Disabled homolog 1, Disabled homolog 1 Drosophila, Scm, Scr, Scrambler, Yot, Yotari, Dab 1
Properties:	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target:	Dab1 (Ser524) Conjugated
Short name:	Conjugated, Dab1 (Ser524) Antibody
Technique:	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	Biotin
Alternative name:	biotinilated coupled, disabled homolog 1 (Drosophila) (Ser524) (Antibody to)
Alternative technique:	antibodies

• #dab
• #antibody
• #ser
• #antibodies
• #biotin
• #disabled
• #gene
• #homolog
• #drosophila