Dab1 (Ser524) Antibody, ALEXA FLUOR 594

Catalog number:	bs-3116R-A594 Buy Now
Price:	384 €
Supplier:	acr
Product name:	Dab1 (Ser524) Antibody, ALEXA FLUOR 594
Quantity:	50 Вµl
Related search:	dab alexa ser antibody antibodies disabled gene homolog deg

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Long name:	ALEXA FLUOR 594 Conjugated, Dab1 (Ser524) Polyclonal Antibody
Also known as:	Anti-Dab1 Ser524 PAb ALEXA FLUOR 594
Category:	Conjugated Primary Antibodies
Conjugated with:	594, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	Dab1 Ser524
Specificity:	This is a highly specific antibody against Dab1 Ser524
Modification:	Phosphorylation
Modification Site:	Ser524
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Source:	KLH conjugated synthetic phosphopeptide derived from human Dab1 around the phosphorylation site of Ser524
Gene ID Number:	1600
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Cross-reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen:	Dab1 also mediates activation of Akt (PKB) by reelin resulting in inhibition of glycogen synthase kinase 3 beta (GSK-3 beta) and decreased phosphorylation of the microtubule-associated protein, Dab1 contains a phosphotyrosine binding (PTB) domain in the amino terminus, Dab1 is an intracellular adapter protein that functions in downstream signaling events initiated by the secreted protein reelin, Dab1 serine 491 is phosphorylated in a Cdk5-dependent manner and regulates, Phenotypically, Reelin-induced signaling during neural cortex development, Src family kinase and c-Abl activities are themselves then stimulated by binding to tyrosine phosphorylated Dab1, Tau, Tyrosine phosphorylation of Dab1 is increased by reelin binding to the Very Low Density Lipoprotein Receptor (VLDLR) and Apolipoprotein E Receptor 2 (ApoER2) through stimulation of Src family kinases, and severe cerebellar hypoplasia, disruption of neuronal migration, likely indirectly, the mutation of this gene produces motor defects and ataxia, Disabled 1 (Dab1) is an 80 kDa protein that is encoded by the Disabled-1 gene locus which is mutated in scrambler and yotari mutant mice
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	590nm/617nm
Synonyms:	Disabled homolog 1, Disabled homolog 1 Drosophila, Scm, Scr, Scrambler, Yot, Yotari, Dab 1
Properties:	ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	594, ALEXA FLUOR®, Alexa Fluor
Conjugated:	Alexa conjugate 1
Gene target:	Dab1 (Ser524)
Short name:	Dab1 (Ser524) Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 594
Alternative name:	ALEXA FLUOR 594, disabled homolog 1 (Drosophila) (Ser524) (Antibody to)
Alternative technique:	antibodies

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