| Long name: |
FITC Conjugated, DOK2 (Tyr351) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DOK2 Tyr351 |
| Specificity: |
Due to the highly conserved nature of this sequence with DOK1, This phosphorylation site is found at Tyr345 in Human, this antibody may react with DOK1 when it is phosphorylated at Tyr362 in Human and Tyr361 in Mouse and Rat, This is a highly specific antibody against DOK2 Tyr351 |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr351 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
320-370/412 |
| Source: |
KLH conjugated synthetic phosphopeptide derived from mouse p56Dok2 around the phosphorylation site of (Tyr351) |
| Gene ID number: |
13449 |
| Swiss Prot: |
O70469 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Attenuates EGF-stimulated MAP kinase activation, DOK2 may modulate the cellular proliferation induced by IL-4, May be involved in modulating Bcr-Abl signaling, They provide a docking platform for the assembly of multimolecular signaling complexes, as well as IL-2 and IL-3, DOK proteins are enzymatically inert adaptor or scaffolding proteins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
p56dok-2 Dok-2 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DOK2 (Tyr351) Conjugated |
| Short name: |
FITC Conjugated, DOK2 (Tyr351) Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, DOK2 (Tyr351) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2991 |
| Gene: |
DOK2 |
More about : DOK2 |
| Long gene name: |
docking protein 2 |
| Synonyms gene name: |
56kD docking protein 2, 56kDa , docking protein 2 |
| Synonyms name: |
downstream of tyrosine kinase 2 |
| Locus: |
8p21, 3 |
| Discovery year: |
1999-02-05 |
| GenBank acession: |
AF034970 |
| Entrez gene record: |
9046 |
| Pubmed identfication: |
9478921 14645010 |
| RefSeq identity: |
NM_003974 |
| Havana BLAST/BLAT: |
OTTHUMG00000131075 |