| Long name: |
Biotin Conjugated, DOK2 (Tyr351) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DOK2 Tyr351 |
| Specificity: |
Due to the highly conserved nature of this sequence with DOK1, This phosphorylation site is found at Tyr345 in Human, this antibody may react with DOK1 when it is phosphorylated at Tyr362 in Human and Tyr361 in Mouse and Rat, This is a highly specific antibody against DOK2 Tyr351 |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr351 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
320-370/412 |
| Source: |
KLH conjugated synthetic phosphopeptide derived from mouse p56Dok2 around the phosphorylation site of (Tyr351) |
| Gene ID number: |
13449 |
| Swiss Prot: |
O70469 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Attenuates EGF-stimulated MAP kinase activation, DOK2 may modulate the cellular proliferation induced by IL-4, May be involved in modulating Bcr-Abl signaling, They provide a docking platform for the assembly of multimolecular signaling complexes, as well as IL-2 and IL-3, DOK proteins are enzymatically inert adaptor or scaffolding proteins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
p56dok-2 Dok-2 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DOK2 (Tyr351) Conjugated |
| Short name: |
Conjugated, DOK2 (Tyr351) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, DOK2 (Tyr351) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2991 |
| Gene: |
DOK2 |
More about : DOK2 |
| Long gene name: |
docking protein 2 |
| Synonyms gene name: |
56kD docking protein 2, 56kDa , docking protein 2 |
| Synonyms name: |
downstream of tyrosine kinase 2 |
| Locus: |
8p21, 3 |
| Discovery year: |
1999-02-05 |
| GenBank acession: |
AF034970 |
| Entrez gene record: |
9046 |
| Pubmed identfication: |
9478921 14645010 |
| RefSeq identity: |
NM_003974 |
| Havana BLAST/BLAT: |
OTTHUMG00000131075 |