CBL2 (Tyr731) Antibody, Biotin Conjugated

Catalog number:	bs-3089R-Biotin Buy Now
Price:	368 €
Supplier:	Bioss Primary Conjugated Antibodies
Product name:	CBL2 (Tyr731) Antibody, Biotin Conjugated
Quantity:	0.1ml
Related search:	cbl antibody tyr gene biotin synonyms oncogene

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Long name:	Biotin Conjugated, CBL2 (Tyr731) Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	Biotinylated
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	CBL2 Tyr731
Specificity:	This is a highly specific antibody against CBL2 Tyr731
Modification:	Phosphorylation
Modification site:	Tyr731
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Source:	KLH conjugated synthetic phosphopeptide derived from human CBL2 around the phosphorylation site of Tyr731
Gene ID number:	867
Tested applications:	IHC-P, WB
Recommended dilutions:	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity:	Mouse, Rat, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	An additional mechanism to attenuate receptor signaling is thought to be achieved by CBLâ, In more recent studies CBL has been shown to be a negative regulator of tyrosine kinase signaling, Targets of CBL include activated protein tyrosine kinases belonging to the Src and Syk/Zap 70 families, The ubiquitin ligase activity of CBL leads to the degradation of tyrosine kinases, such as PI 3K and Vav, thus attenuating the signal of receptors, &euro, &trade, The proto oncogene c CBL was initially identified as the cellular homologue of v CBL oncogene that induces pre B cell lymphomas and myeloid leukemias in mice, s interaction with downstream targets of tyrosine kinases
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Synonyms:	RNF55 c-Cbl
Properties:	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target:	CBL2 (Tyr731) Conjugated
Short name:	Conjugated, CBL2 (Tyr731) Antibody
Technique:	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	Biotin
Alternative name:	biotinilated coupled, CBL2 (Tyr731) (Antibody to)
Alternative technique:	antibodies
Identity:	1541
Gene:	CBL | More about : CBL
Long gene name:	Cbl proto-oncogene
Synonyms gene:	CBL2
Synonyms gene name:	Cas-Br-M (murine) ecotropic retroviral transforming sequence Cbl proto-oncogene, E3 ubiquitin protein ligase
Synonyms name:	oncogene CBL2
Locus:	11q23, 3
Discovery year:	1989-06-30
GenBank acession:	X57110
Entrez gene record:	867
Pubmed identfication:	2013228
RefSeq identity:	NM_005188
Classification:	Ring finger proteins
Havana BLAST/BLAT:	OTTHUMG00000166170
Locus Specific Databases:	LRG_608

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• #oncogene