CBL2 (Tyr731) Antibody, ALEXA FLUOR 594

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Catalog number: bs-3089R-A594
Price: 350 €
Supplier: Bioss Primary Conjugated Antibodies.
Product name: CBL2 (Tyr731) Antibody, ALEXA FLUOR 594
Quantity: 100ul
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Long name: ALEXA FLUOR 594 Conjugated, CBL2 (Tyr731) Polyclonal Antibody
Also known as: Anti-CBL2 Tyr731 PAb ALEXA FLUOR 594
Category: Conjugated Primary Antibodies
Conjugated with: 594, ALEXA FLUOR®
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: CBL2 Tyr731
Specificity: This is a highly specific antibody against CBL2 Tyr731
Modification: Phosphorylation
Modification Site: Tyr731
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Source: KLH conjugated synthetic phosphopeptide derived from human CBL2 around the phosphorylation site of Tyr731
Gene ID Number: 867
Tested applications: IF(IHC-P)
Recommended dilutions: IF(IHC-P)(1:50-200)
Crossreactivity: Mouse, Rat, Human
Cross-reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen: An additional mechanism to attenuate receptor signaling is thought to be achieved by CBLâ, In more recent studies CBL has been shown to be a negative regulator of tyrosine kinase signaling, Targets of CBL include activated protein tyrosine kinases belonging to the Src and Syk/Zap 70 families, The ubiquitin ligase activity of CBL leads to the degradation of tyrosine kinases, such as PI 3K and Vav, thus attenuating the signal of receptors, &euro, &trade, The proto oncogene c CBL was initially identified as the cellular homologue of v CBL oncogene that induces pre B cell lymphomas and myeloid leukemias in mice, s interaction with downstream targets of tyrosine kinases
Purification: Purified by Protein A
Storage conditions: 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission: 590nm/617nm
Synonyms: RNF55 c-Cbl
Properties: ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation: 594, ALEXA FLUOR®, Alexa Fluor
Conjugated: Alexa conjugate 1
Gene target: CBL2 (Tyr731)
Short name: CBL2 (Tyr731) Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Label: ALEXA FLUOR 594
Alternative name: ALEXA FLUOR 594, CBL2 (Tyr731) (Antibody to)
Alternative technique: antibodies
Identity: 1541
Gene: CBL | More about : CBL
Long gene name: Cbl proto-oncogene
Synonyms gene: CBL2
Synonyms gene name: Cas-Br-M (murine) ecotropic retroviral transforming sequence Cbl proto-oncogene, E3 ubiquitin protein ligase
Synonyms name: oncogene CBL2
Locus: 11q23, 3
Discovery year: 1989-06-30
GenBank acession: X57110
Entrez gene record: 867
Pubmed identfication: 2013228
RefSeq identity: NM_005188
Classification: Ring finger proteins
Havana BLAST/BLAT: OTTHUMG00000166170
Locus Specific Databases: LRG_608

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