CBL2 (Tyr731) Antibody

Catalog number:	bs-3089R Buy Now
Price:	350 €
Supplier:	Bioss Primary Conjugated Antibodies
Product name:	CBL2 (Tyr731) Antibody
Quantity:	0.1ml
Related search:	cbl tyr antibody gene oncogene synonyms deg

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Long name:	CBL2 (Tyr731) Primary Polyclonal Antibody
Also known as:	CBL2 (Tyr731) PAb
Category:	Primary Antibodies
Conjugation:	Unconjugated
Target Antigen:	CBL2 Tyr731
Specificity:	This is a highly specific antibody against CBL2 Tyr731
Modification(s):	Phosphorylation
Modification site(s):	Tyr731
Clonality:	Polyclonal antibody
Clone number:	Polyclonal antibody
Concentration:	1ug per 1ul
Source:	KLH conjugated synthetic phosphopeptide derived from human CBL2 around the phosphorylation site of Tyr731
Gene ID number:	867
Tested Applications:	IF(IHC-P), IHC-P, WB
Recommended dilutions:	IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity:	Mouse, Rat, Human
Cross reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen:	An additional mechanism to attenuate receptor signaling is thought to be achieved by CBLâ, In more recent studies CBL has been shown to be a negative regulator of tyrosine kinase signaling, Targets of CBL include activated protein tyrosine kinases belonging to the Src and Syk/Zap 70 families, The ubiquitin ligase activity of CBL leads to the degradation of tyrosine kinases, such as PI 3K and Vav, thus attenuating the signal of receptors, &euro, &trade, The proto oncogene c CBL was initially identified as the cellular homologue of v CBL oncogene that induces pre B cell lymphomas and myeloid leukemias in mice, s interaction with downstream targets of tyrosine kinases
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names:	4732447J05Rik, C CBL, CBL 2, CBL2 Tyr731, CBL2 Tyr731, CBL_HUMAN, Cas-Br-M murine ecotropic retroviral transforming sequence, Casitas B lineage lymphoma proto oncogene, Oncogene CBL2, Proto oncogene c CBL, RGD1561386, RING finger protein 55, RNF55v Signal transduction protein CBL, p-CBL2 Tyr731, p-CBL2 Y731, C CBL Tyr731, E3 ubiquitin protein ligase CBL
Properties:	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target:	CBL2 (Tyr731)
Short name:	CBL2 (Tyr731) Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Alternative name:	CBL2 (Tyr731) (Antibody to)
Alternative technique:	antibodies
Identity:	1541
Gene:	CBL | More about : CBL
Long gene name:	Cbl proto-oncogene
Synonyms gene:	CBL2
Synonyms gene name:	Cas-Br-M (murine) ecotropic retroviral transforming sequence Cbl proto-oncogene, E3 ubiquitin protein ligase
Synonyms:	RNF55 c-Cbl
Synonyms name:	oncogene CBL2
Locus:	11q23, 3
Discovery year:	1989-06-30
GenBank acession:	X57110
Entrez gene record:	867
Pubmed identfication:	2013228
RefSeq identity:	NM_005188
Classification:	Ring finger proteins
Havana BLAST/BLAT:	OTTHUMG00000166170
Locus Specific Databases:	LRG_608

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