Ack1 (Tyr284) Antibody, Cy5.5 Conjugated

Catalog number:	bs-3045R-Cy5.5 Buy Now
Price:	332 €
Supplier:	Bioss Primary Conjugated Antibodies.
Product name:	Ack1 (Tyr284) Antibody, Cy5.5 Conjugated
Quantity:	100ul
Related search:	tyr ack antibody antibodies conjugated kinase protein migration

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Long name:	Cy5, 5 Conjugated, Ack1 (Tyr284) Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	Cy5, 5, 5, Cy5
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	Ack1 Tyr284
Specificity:	This phosphorylation site is homologous to the Tyr284 site in Mouse and Rat, This is a highly specific antibody against Ack1 Tyr284
Modification:	Phosphorylation
Modification site:	Tyr284
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen_range:	260-310/1055
Subcellular location:	Membrane bound, Nucleus
Source:	KLH conjugated synthetic phosphopeptide derived from mouse Ack1 around the phosphorylation site of Tyr284
Gene ID number:	51789
Swiss Prot:	O54967
Tested applications:	IF(IHC-P), FCM
Recommended dilutions:	IF(IHC-P)(1:50-200), FCM(1:20-100)
Crossreactivity:	Mouse, Rat, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	AR, Activates AKT1 by phosphorylating it on 'Tyr-176', Binds to both poly- and mono-ubiquitin and regulates ligand-induced degradation of EGFR, Confers metastatic properties on cancer cells and promotes tumor growth by negatively regulating tumor suppressor such as WWOX and positively regulating pro-survival factors such as AKT1 and AR, Contributes to the control of AXL receptor levels, Downstream effector of CDC42 which mediates CDC42-dependent cell migration via phosphorylation of BCAR1, Implicated in trafficking and clathrin-mediated endocytosis through binding to epidermal growth factor receptor (EGFR) and clathrin, MCF2, May be involved both in adult synaptic function and plasticity and in brain development, Phosphorylates AKT1, Phosphorylates AR on 'Tyr-267' and 'Tyr-363' thereby promoting its recruitment to androgen-responsive enhancers (AREs), Phosphorylates MCF2, Phosphorylates WWOX on 'Tyr-287', Transduces extracellular signals to cytosolic and nuclear effectors, WASL and WWOX, cell growth and proliferation, cell survival, thereby contributing to the accumulation of EGFR at the limiting membrane of early endosomes, thereby enhancing its activity as a guanine nucleotide exchange factor (GEF) toward Rho family proteins, Non-receptor tyrosine-protein and serine/threonine-protein kinase that is implicated in cell spreading and migration
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission:	675nm/694nm
Synonyms:	Ack-1, Ack1, Activated CDC42 kinase 1, Cdgip, Non-receptor protein tyrosine kinase Ack, Pyk1, Tnk2, Tyrosine kinase non-receptor protein 2, Ack
Properties:	Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Conjugated:	These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths
Gene target:	Ack1 (Tyr284) Conjugated
Short name:	Conjugated, Ack1 (Tyr284) Antibody
Technique:	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	5, Cy5
Alternative name:	cyanine 5, 5 coupled, Ack1 (Tyr284) (Antibody to)
Alternative technique:	antibodies

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