| Long name: |
ALEXA FLUOR 488 Conjugated, RBPJK Polyclonal Antibody |
| Also known as: |
Anti-RBPJK PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
RBPJK |
| Specificity: |
This is a highly specific antibody against RBPJK |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
100-150/500 |
| Subcellular location: |
Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RBPJK |
| Gene ID Number: |
3516 |
| Swiss Prot: |
Q06330 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Acts as a transcriptional repressor when it is not associated with Notch proteins, Binds specifically to methylated DNA, Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence, When associated with some NICD product of Notch proteins (Notch intracellular domain), a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations, it acts as a transcriptional activator that activates transcription of Notch target genes, respectively, Transcriptional regulator that plays a central role in Notch signaling |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
SUH IGKJRB RBPJK KBF2 RBP-J CBF1 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the RBPJK Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
RBPJK |
| Short name: |
RBPJK Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, RBPJK (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
5724 |
| Gene: |
RBPJ |
More about : RBPJ |
| Long gene name: |
recombination signal binding protein for immunoglobulin kappa J region |
| Synonyms gene: |
IGKJRB1 RBPSUH |
| Synonyms gene name: |
recombining binding protein suppressor of hairless (Drosophila) |
| Synonyms name: |
suppressor of hairless homolog (Drosophila) |
| Locus: |
4p15, 2 |
| Discovery year: |
1993-04-23 |
| GenBank acession: |
L07872 |
| Entrez gene record: |
3516 |
| Pubmed identfication: |
8406481 9290259 16354684 |
| RefSeq identity: |
NM_015874 |
| Havana BLAST/BLAT: |
OTTHUMG00000097793 |