| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
RBPJK |
| Specificity: |
This antibody reacts specifically with RBPJK |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human RBPJK |
| Gene ID: |
3516 |
| Swiss Prot: |
Q06330 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Acts as a transcriptional repressor when it is not associated with Notch proteins, Binds specifically to methylated DNA, Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence, When associated with some NICD product of Notch proteins (Notch intracellular domain), a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations, it acts as a transcriptional activator that activates transcription of Notch target genes, respectively, Transcriptional regulator that plays a central role in Notch signaling |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
SUH IGKJRB RBPJK KBF2 RBP-J CBF1 |
| Also known as: |
RBPJK Polyclonal Antibody |
| Other name: |
Anti-RBPJK Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
RBPJK |
| Short name: |
Anti-RBPJK (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-RBPJK (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
5724 |
| Gene: |
RBPJ |
More about : RBPJ |
| Long gene name: |
recombination signal binding protein for immunoglobulin kappa J region |
| Synonyms gene: |
IGKJRB1 RBPSUH |
| Synonyms gene name: |
recombining binding protein suppressor of hairless (Drosophila) |
| Synonyms name: |
suppressor of hairless homolog (Drosophila) |
| Locus: |
4p15, 2 |
| Discovery year: |
1993-04-23 |
| GenBank acession: |
L07872 |
| Entrez gene record: |
3516 |
| Pubmed identfication: |
8406481 9290259 16354684 |
| RefSeq identity: |
NM_015874 |
| Havana BLAST/BLAT: |
OTTHUMG00000097793 |