| Long name: |
RBPJK Primary Polyclonal Antibody |
| Also known as: |
RBPJK PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
RBPJK |
| Specificity: |
This is a highly specific antibody against RBPJK |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
100-150/500 |
| Subcellular location: |
Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RBPJK |
| Gene ID number: |
3516 |
| Swiss Prot: |
Q06330 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Acts as a transcriptional repressor when it is not associated with Notch proteins, Binds specifically to methylated DNA, Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence, When associated with some NICD product of Notch proteins (Notch intracellular domain), a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations, it acts as a transcriptional activator that activates transcription of Notch target genes, respectively, Transcriptional regulator that plays a central role in Notch signaling |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
AOS3, CBF-1, CBF1, IGKJRB, IGKJRB1, J kappa-recombination signal-binding protein, KBF2, RBP-J, RBP-J kappa, RBP-JK, RBPJ, RBPJK, RBPSUH, Recombining binding protein suppressor of hairless, Renal carcinoma antigen NY-REN-30, csl, SUH |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
RBPJK |
| Short name: |
RBPJK Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RBPJK (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
5724 |
| Gene: |
RBPJ |
More about : RBPJ |
| Long gene name: |
recombination signal binding protein for immunoglobulin kappa J region |
| Synonyms gene: |
IGKJRB1 RBPSUH |
| Synonyms gene name: |
recombining binding protein suppressor of hairless (Drosophila) |
| Synonyms: |
SUH IGKJRB RBPJK KBF2 RBP-J CBF1 |
| Synonyms name: |
suppressor of hairless homolog (Drosophila) |
| Locus: |
4p15, 2 |
| Discovery year: |
1993-04-23 |
| GenBank acession: |
L07872 |
| Entrez gene record: |
3516 |
| Pubmed identfication: |
8406481 9290259 16354684 |
| RefSeq identity: |
NM_015874 |
| Havana BLAST/BLAT: |
OTTHUMG00000097793 |