CK10 Antibody, ALEXA FLUOR 350

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Catalog number: bs-2700R-A350
Price: 332 €
Supplier: Bioss Primary Conjugated Antibodies.
Product name: CK10 Antibody, ALEXA FLUOR 350
Quantity: 100ul
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Long name: ALEXA FLUOR 350 Conjugated, CK10 Polyclonal Antibody
Also known as: Anti-CK10 PAb ALEXA FLUOR 350
Category: Conjugated Primary Antibodies
Conjugated with: 350, ALEXA FLUOR®
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: CK10
Specificity: This is a highly specific antibody against CK10
Modification: Unmodified
Modification Site: None
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Immunogen range: 140-190/584
Subcellular location: Cytoplasm
Source: This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CK10
Gene ID Number: 3858
Swiss Prot: P13645
Tested applications: IF(IHC-P)
Recommended dilutions: IF(IHC-P)(1:50-200)
Crossreactivity: Mouse, Rat, Human
Cross-reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen: A number of alleles are known that mainly differ in the Gly-rich region (positions 490-560), AEI resembles clinical and histologic features of both epidermolytic hyperkeratosis and ichthyosis bullosa of Siemens, At birth, Cytokeratin 10 is generally associated with keratin 1, Defects in cytokeratin 10 are a cause of epidermolytic hyperkeratosis (EHK), Defects in cytokeratin 10 are also a cause of annular epidermolytic ichthyosis (AEI), EHK is an hereditary skin disorder characterized by blistering and a marked thickening of the stratum corneum, It is seen in all suprabasal cell layers including stratum corneum, Transmission is autosomal dominant, Within a few weeks, affected individuals usually present with redness, also known as bullous congenital ichthyosiform erythroderma (BCIE) or bullous erythroderma ichthyosiformis congenita of Brocq, also known as cyclic ichthyosis with epidermolytic hyperkeratosis, blisters and superficial erosions due to cytolysis, but most cases are sporadic, the erythroderma and blister formation diminish and hyperkeratoses develop, Cytokeratin 10 is a heterotetramer of two type I and two type II keratins
Purification: Purified by Protein A
Storage conditions: 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission: 343nm/442nm
Synonyms: K10 CK10
Properties: ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation: ALEXA FLUOR 350, Alexa Fluor
Gene target: CK10
Short name: CK10 Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Label: ALEXA FLUOR 350
Alternative name: ALEXA FLUOR 350, CK10 (Antibody to)
Alternative technique: antibodies
Identity: 6413
Gene: KRT10 | More about : KRT10
Long gene name: keratin 10
Synonyms gene: KPP
Synonyms gene name: keratosis palmaris et plantaris keratin 10, type I
Synonyms name: cytokeratin 10 epidermolytic hyperkeratosis
Locus: 17q21, 2
Discovery year: 1988-08-12
GenBank acession: J04029
Entrez gene record: 3858
Pubmed identfication: 2461420 16831889
RefSeq identity: NM_000421
Classification: Keratins, type I
Havana BLAST/BLAT: OTTHUMG00000133368

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