| Long name: |
IL1 Receptor I Primary Polyclonal Antibody |
| Also known as: |
IL1 Receptor I PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
IL-1R1 |
| Specificity: |
This is a highly specific antibody against IL-1R1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
510-545/569 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human IL-1R1 |
| Gene ID number: |
3554 |
| Swiss Prot: |
P14778 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
After binding to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex, IL1B and IL1RN, MAPK and other pathways, MYD88, Signaling involves the recruitment of adapter molecules such as TOLLIP, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits, Receptor for IL1A |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CD121 antigen-like family member A, CD121A, D2S1473, IL-1R-1, IL-1R-alpha, IL-1RT-1, IL-1RT1, IL1R, IL1R1, IL1RA, IL1RT1, Interleukin-1 receptor alpha, Interleukin-1 receptor type 1, Interleukin-1 receptor type I, P80 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
IL1 Receptor I |
| Short name: |
IL1 Receptor I Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
IL1 Receptor I (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
5991 |
| Gene: |
IL1A |
More about : IL1A |
| Long gene name: |
interleukin 1 alpha |
| Synonyms gene: |
IL1 |
| Synonyms: |
IL1F1 IL-1A IL1-ALPHA |
| Synonyms name: |
preinterleukin 1 alpha hematopoietin-1 pro-interleukin-1-alpha |
| Locus: |
2q14, 1 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
M28983 |
| Entrez gene record: |
3552 |
| Pubmed identfication: |
8188271 2989698 |
| RefSeq identity: |
NM_000575 |
| Classification: |
Endogenous ligands Interleukins |
| Havana BLAST/BLAT: |
OTTHUMG00000131315 |