| Long name: |
FITC Conjugated, IL1 Receptor I Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
IL-1R1 |
| Specificity: |
This is a highly specific antibody against IL-1R1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
510-545/569 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human IL-1R1 |
| Gene ID number: |
3554 |
| Swiss Prot: |
P14778 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
After binding to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex, IL1B and IL1RN, MAPK and other pathways, MYD88, Signaling involves the recruitment of adapter molecules such as TOLLIP, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits, Receptor for IL1A |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
IL1F1 IL-1A IL1-ALPHA |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
IL1 Receptor I Conjugated |
| Short name: |
FITC Conjugated, IL1 Receptor I Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, IL1 Receptor I (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
5991 |
| Gene: |
IL1A |
More about : IL1A |
| Long gene name: |
interleukin 1 alpha |
| Synonyms gene: |
IL1 |
| Synonyms name: |
preinterleukin 1 alpha hematopoietin-1 pro-interleukin-1-alpha |
| Locus: |
2q14, 1 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
M28983 |
| Entrez gene record: |
3552 |
| Pubmed identfication: |
8188271 2989698 |
| RefSeq identity: |
NM_000575 |
| Classification: |
Endogenous ligands Interleukins |
| Havana BLAST/BLAT: |
OTTHUMG00000131315 |