| Long name: |
ALEXA FLUOR 350 Conjugated, ICOS/CD278 Polyclonal Antibody |
| Also known as: |
Anti-ICOS/CD278 PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ICOS/CD278 |
| Specificity: |
This is a highly specific antibody against ICOS/CD278 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
40-90/199 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ICOS |
| Gene ID Number: |
29851 |
| Swiss Prot: |
Q9Y6W8 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Does not up-regulate the production of interleukin-2, Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens, Plays a critical role in CD40-mediated class switching of immunoglobin isotypes (By similarity), Prevents the apoptosis of pre-activated T-cells, and effective help for antibody secretion by B-cells, but superinduces the synthesis of interleukin-10, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, Enhances all basic T-cell responses to a foreign antigen |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
AILIM CD278 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
ICOS/CD278 |
| Short name: |
ICOS/CD278 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, inducible T-cell co-stimulator/CD278 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Extracellular, ICOS and IDBG-643378 and ENSBTAG00000021596 and 507026, ICOS and IDBG-79246 and ENSG00000163600 and 29851, Icos and IDBG-159737 and ENSMUSG00000026009 and 54167, protein binding, this GO :0002517 and T cell tolerance induction and biological process this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0031295 and T cell costimulation and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding, inducible T-cell co-stimulator |
| Identity: |
5351 |
| Gene: |
ICOS |
More about : ICOS |
| Long gene name: |
inducible T-cell costimulator |
| Synonyms name: |
activation-inducible lymphocyte immunomediatory molecule |
| Locus: |
2q33, 2 |
| Discovery year: |
2000-02-29 |
| GenBank acession: |
AB023135 |
| Entrez gene record: |
29851 |
| Pubmed identfication: |
9930702 10617205 |
| RefSeq identity: |
NM_012092 |
| Classification: |
CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000132880 |
| Locus Specific Databases: |
ICOSbase: Mutation registry for ICOS deficiency LRG_65 |