| Long name: |
ICOS-L/B7-H2/CD275 Primary Polyclonal Antibody |
| Also known as: |
ICOS-L/B7-H2/CD275 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
ICOS-L/B7-H2/CD275 |
| Specificity: |
This is a highly specific antibody against ICOS-L/B7-H2/CD275 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
1-50/302 |
| Subcellular location: |
Cell membrane |
| Source: |
KLH conjugated synthetic peptide derived from Rat ICOS-L |
| Gene ID number: |
23308 |
| Swiss Prot: |
O75144 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Rat |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Acts as a costimulatory signal for T-cell proliferation and cytokine secretion, Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity), induces also B-cell proliferation and differentiation into plasma cells, Ligand for the T-cell-specific cell surface receptor ICOS |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
B7 homolog 2, B7-H2, B7-like protein Gl50, B7-related protein 1, B7RP-1, B7RP1, CD275, GL50, ICOS ligand, ICOS-L, ICOSL, ICOSLG, KIAA0653, LICOS, B7H2 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ICOS-L/B7-H2/CD275 |
| Short name: |
ICOS-L/B7-H2/CD275 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
inducible T-cell co-stimulator-L/B7-H2/CD275 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Extracellular, ICOS and IDBG-643378 and ENSBTAG00000021596 and 507026, ICOS and IDBG-79246 and ENSG00000163600 and 29851, Icos and IDBG-159737 and ENSMUSG00000026009 and 54167, protein binding, this GO :0002517 and T cell tolerance induction and biological process this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0031295 and T cell costimulation and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding, inducible T-cell co-stimulator |
| Identity: |
17087 |
| Gene: |
ICOSLG |
More about : ICOSLG |
| Long gene name: |
inducible T-cell costimulator ligand |
| Synonyms gene: |
ICOSL |
| Synonyms: |
KIAA0653 GL50 B7-H2 B7RP-1 B7H2 B7RP1 ICOS-L CD275 |
| Synonyms name: |
B7-related protein 1 B7 homologue 2 B7 homolog 2 |
| Locus: |
21q22, 3 |
| Discovery year: |
2003-12-12 |
| GenBank acession: |
AB014553 |
| Entrez gene record: |
23308 |
| Pubmed identfication: |
9734811 11007762 |
| RefSeq identity: |
NM_015259 |
| Classification: |
Endogenous ligands C2-set domain containing CD molecules V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000086920 |