| Long name: |
FITC Conjugated, TWIST protein Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TWIST |
| Specificity: |
This is a highly specific antibody against TWIST |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
108-150/202 |
| Subcellular location: |
Nucleus |
| Source: |
KLH conjugated synthetic peptide derived from human TWIST |
| Gene ID number: |
7291 |
| Swiss Prot: |
Q15672 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Activates transcription as a heterodimer with E proteins, Also represses expression of proinflammatory cytokines such as TNFA and IL1B, Heterodimerization is also required for osteoblast differentiation, Homodimers induce expression of FGFR2 and POSTN while heterodimers repress FGFR2 and POSTN expression and induce THBS1 expression, Inhibits myogenesis by sequestrating E proteins, Regulates cranial suture patterning and fusion, Regulates gene expression differentially, Represses the activity of the circadian transcriptional activator: NPAS2-ARNTL/BMAL1 heterodimer (By similarity), This interaction probably involves the basic domains of both proteins, and inhibiting DNA-binding by MYOD1 through physical interaction, depending on dimer composition, inhibiting trans-activation by MEF2, Acts as a transcriptional regulator |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
SCS H-twist BPES2 bHLHa38 CRS1 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TWIST protein Conjugated |
| Short name: |
FITC Conjugated, TWIST protein Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, TWIST protein (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12428 |
| Gene: |
TWIST1 |
More about : TWIST1 |
| Long gene name: |
twist family bHLH transcription factor 1 |
| Synonyms gene: |
ACS3 BPES3 TWIST CRS |
| Synonyms gene name: |
blepharophimosis, epicanthus inversus and ptosis 3 acrocephalosyndactyly 3 twist homolog 1 (Drosophila) twist basic helix-loop-helix transcription factor 1 craniosynostosis |
| Synonyms name: |
Saethre-Chotzen syndrome |
| Locus: |
7p21, 1 |
| Discovery year: |
1997-07-01 |
| GenBank acession: |
U80998 |
| Entrez gene record: |
7291 |
| Pubmed identfication: |
8995765 11474656 17343269 |
| RefSeq identity: |
NM_000474 |
| Classification: |
Basic helix-loop-helix proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000090821 |