| Long name: |
ALEXA FLUOR 647 Conjugated, TWIST protein Polyclonal Antibody |
| Also known as: |
Anti-TWIST PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TWIST |
| Specificity: |
This is a highly specific antibody against TWIST |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
108-150/202 |
| Subcellular location: |
Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TWIST |
| Gene ID Number: |
7291 |
| Swiss Prot: |
Q15672 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Activates transcription as a heterodimer with E proteins, Also represses expression of proinflammatory cytokines such as TNFA and IL1B, Heterodimerization is also required for osteoblast differentiation, Homodimers induce expression of FGFR2 and POSTN while heterodimers repress FGFR2 and POSTN expression and induce THBS1 expression, Inhibits myogenesis by sequestrating E proteins, Regulates cranial suture patterning and fusion, Regulates gene expression differentially, Represses the activity of the circadian transcriptional activator: NPAS2-ARNTL/BMAL1 heterodimer (By similarity), This interaction probably involves the basic domains of both proteins, and inhibiting DNA-binding by MYOD1 through physical interaction, depending on dimer composition, inhibiting trans-activation by MEF2, Acts as a transcriptional regulator |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
SCS H-twist BPES2 bHLHa38 CRS1 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the TWIST protein Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
TWIST protein |
| Short name: |
TWIST protein Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, TWIST protein (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12428 |
| Gene: |
TWIST1 |
More about : TWIST1 |
| Long gene name: |
twist family bHLH transcription factor 1 |
| Synonyms gene: |
ACS3 BPES3 TWIST CRS |
| Synonyms gene name: |
blepharophimosis, epicanthus inversus and ptosis 3 acrocephalosyndactyly 3 twist homolog 1 (Drosophila) twist basic helix-loop-helix transcription factor 1 craniosynostosis |
| Synonyms name: |
Saethre-Chotzen syndrome |
| Locus: |
7p21, 1 |
| Discovery year: |
1997-07-01 |
| GenBank acession: |
U80998 |
| Entrez gene record: |
7291 |
| Pubmed identfication: |
8995765 11474656 17343269 |
| RefSeq identity: |
NM_000474 |
| Classification: |
Basic helix-loop-helix proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000090821 |