| Long name: |
ALEXA FLUOR 647 Conjugated, MDC1 Polyclonal Antibody |
| Also known as: |
Anti-MDC1 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
MDC1 |
| Specificity: |
This is a highly specific antibody against MDC1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
45-90/2089 |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MDC1 |
| Gene ID Number: |
9656 |
| Swiss Prot: |
Q14676 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
ATM and CHEK2 may also be activated independently by a parallel pathway mediated by TP53BP1, Also required for downstream events subsequent to the recruitment of these proteins, CHEK1 and CHEK2 kinases, May serve as a scaffold for the recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage marked by 'Ser-139' phosphorylation of histone H2AFX, These include phosphorylation and activation of the ATM, and stabilization of TP53 and apoptosis, Required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
NFBD1 KIAA0170 Em:AB023051, 5 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the MDC1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
MDC1 |
| Short name: |
MDC1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, mediator on Desoxyribonucleic acid-damage checkpoint 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
FHA domain binding, MDC1 and IDBG-634528 and ENSBTAG00000025526 and 511168, MDC1 and IDBG-76700 and ENSG00000137337 and 9656, Mdc1 and IDBG-179187 and ENSMUSG00000061607 and 240087, NFBD1, nuclei, this GO :0000724 and double-strand break repair via homolo this GO us recombination and biological process this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005694 and chromosome and cellular component this GO :0005925 and focal adhesion and cellular component this GO :0006281 and DNA repair and biological process this GO :0006302 and double-strand break repair and biological process this GO :0008022 and protein C-terminus binding and molecular function this GO :0031573 and intra-S DNA damage checkpoint and biological process this GO :0070975 and FHA domain binding and molecular function, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0008022 : protein C-terminus binding and also this GO :0070975 : FHA domain binding, this GO :0008022 : protein C-terminus binding, this GO :0070975 : FHA domain binding, mediator of DNA-damage checkpoint 1 |
| Identity: |
21163 |
| Gene: |
MDC1 |
More about : MDC1 |
| Long gene name: |
mediator of DNA damage checkpoint 1 |
| Synonyms gene name: |
mediator of DNA-damage checkpoint 1 |
| Locus: |
6p21, 33 |
| Discovery year: |
2003-05-21 |
| GenBank acession: |
D79992 |
| Entrez gene record: |
9656 |
| Pubmed identfication: |
10975465 12607005 |
| RefSeq identity: |
NM_014641 |
| Havana BLAST/BLAT: |
OTTHUMG00000031075 |