| Long name: |
ALEXA FLUOR 488 Conjugated, Ki-67 (Proliferation Marker) Antibody |
| Also known as: |
Anti-Ki-67 proliferation Marker PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Ki-67 proliferation Marker |
| Specificity: |
This is a highly specific antibody against Ki-67 proliferation Marker |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
1250-1300/3256 |
| Subcellular location: |
Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Ki67 |
| Gene ID Number: |
4288 |
| Swiss Prot: |
P46013 |
| Tested applications: |
IF(ICC), IF(IHC-P) |
| Recommended dilutions: |
IF(ICC)(1:50-200), IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
G2 and M phase), In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index, It is absent in resting (G0) cells, Ki67 are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index), Ki67 is routinely used as a neuronal marker of cell cycling and proliferation, S, The correlation between low Ki67 index and histologically low grade tumours is strong, expressed by proliferating cells in all phases of the active cell cycle (G1, Proliferation Marker Ki67 antigen is the prototypic cell cycle related nuclear protein |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
Antigen KI-67, MIB-, MIB-1, MKI67, PPP1R15, KIA |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Ki-67 (Proliferation Marker) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Ki-67 (Proliferation |
| Short name: |
Ki-67 (Proliferation Marker) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, Ki-67 (expantion detection labelled) (Antibody to) |
| Alternative technique: |
antibodies |