| Long name: |
ALEXA FLUOR 647 Conjugated, Yellow fever virus envelope glycoprotein E Antibody |
| Also known as: |
Anti-Yellow fever virus envelope glycoprotein E PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Yellow fever virus envelope glycoprotein E |
| Specificity: |
This is a highly specific antibody against Yellow fever virus envelope glycoprotein E |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
650-700/3411 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from Yellow fever virus envelope glycoprotein E (IIVGRGDSRLTY) |
| Gene ID Number: |
1502173 |
| Swiss Prot: |
P03314 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Virus |
| Cross-reactive species details: |
Yellow fever virus |
| Background of the antigen: |
After cleavage by host furin, After cleavage of prM, Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis, Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes, NS2A-NS2B, NS2B-NS3, NS3 RNA helicase binds RNA and unwinds dsRNA in the 3' to 5' direction (By similarity), NS3 serine protease, NS3-NS4A, NS4A-2K and NS4B-NS5, NTPase and RNA helicase, Non-structural protein 1 is involved in virus replication and regulation of the innate immune response, Non-structural protein 2A may be involved viral RNA replication and capsid assembly, Non-structural protein 2B is a required cofactor for the serine protease function of NS3, Non-structural protein 4A induces host endoplasmic reticulum membrane rearrangements leading to the formation of virus-induced membranous vesicles hosting the dsRNA and polymerase, Serine protease NS3 displays three enzymatic activities: serine protease, Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E, The capsid encapsulates the genomic RNA (By similarity), envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity), functioning as a replication complex, in association with NS2B, performs its autocleavage and cleaves the polyprotein at dibasic sites in the cytoplasm: C-prM, prM acts as a chaperone for envelope protein E during intracellular virion assembly by masking and inactivating envelope protein E fusion peptide, prM is matured in the last step of virion assembly, presumably to avoid catastrophic activation of the viral fusion peptide induced by the acidic pH of the trans-Golgi network, the pr peptide is released in the extracellular medium and small envelope protein M and envelope protein E homodimers are dissociated (By similarity), Capsid protein C self-assembles to form an icosahedral capsid about 30 nm in diameter |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
Genome polyprotein |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the fever virus envelope glycoprotein E Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
fever virus envelope glycoprotein E |
| Short name: |
fever virus envelope glycoprotein E Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, Yellow fever virus envelope glycoprotein E (Antibody to) |
| Alternative technique: |
antibodies |