| Long name: |
FITC Conjugated, FAIM3 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
FAIM3 |
| Specificity: |
This is a highly specific antibody against FAIM3 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
80-130/390 |
| Subcellular location: |
Cell membrane, Secreted, Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human FAIM3 |
| Gene ID number: |
9214 |
| Swiss Prot: |
O60667 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation, Protects cells from FAS-, Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL, rather than blocking apoptotic signals downstream, May play a role in the immune system processes |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
TOSO |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
FAIM3 Conjugated |
| Short name: |
FITC Conjugated, FAIM3 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, member 6) apoptotic inhibitory molecule 3 (Antibody to), Fas (TNF receptor superfamily |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Extracellular, FAIM3 and IDBG-106292 and ENSG00000162894 and 9214, FAIM3 and IDBG-629197 and ENSBTAG00000019796 and 511564, FCMR and TOSO, Faim3 and IDBG-190537 and ENSMUSG00000042474 and 69169, this GO :0002376 and immune system process and biological process this GO :0005576 and extracellular region and cellular component this GO :0006968 and cellular defense response and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0043066 and negative regulation of apoptotic process and biological process, Fas apoptotic inhibitory molecule 3 |
| Identity: |
14315 |
| Gene: |
FCMR |
More about : FCMR |
| Long gene name: |
Fc fragment of IgM receptor |
| Synonyms gene: |
FAIM3 |
| Synonyms gene name: |
Fas apoptotic inhibitory molecule 3 |
| Locus: |
1q32, 1 |
| Discovery year: |
2005-04-04 |
| GenBank acession: |
AF057557 |
| Entrez gene record: |
9214 |
| Pubmed identfication: |
9586636 1563211 25888699 |
| RefSeq identity: |
NM_005449 |
| Classification: |
Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000036457 |