PCNA [Proliferation Marker] Antibody, FITC Conjugated

Catalog number:	bs-2007R-FITC Buy Now
Price:	818 €
Supplier:	MBS Polyclonals_1
Product name:	PCNA [Proliferation Marker] Antibody, FITC Conjugated
Quantity:	50ug
Related search:	antibody dna conjugated gene replication fluorescent year

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Long name:	FITC Conjugated, PCNA [Proliferation Marker] Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	Anti-FITC Antibody
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	PCNA [proliferation Marker]
Specificity:	This is a highly specific antibody against PCNA [proliferation Marker]
Modification:	Unmodified
Modification site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen_range:	220-261/261
Subcellular location:	Nucleus
Source:	KLH conjugated synthetic peptide derived from human PCNA
Gene ID number:	5111
Swiss Prot:	P12004
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	APEX2 activities, Acts as a loading platform to recruit DDR proteins that allow completion of DNA replication after DNA damage and promote postreplication repair: Monoubiquitinated PCNA leads to recruitment of translesion (TLS) polymerases, Has to be loaded onto DNA in order to be able to stimulate APEX2, Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA repair and DNA damage tolerance pathways, but not apurinic-apyrimidinic (AP) endonuclease, while 'Lys-63'-linked polyubiquitination of PCNA is involved in error-free pathway and employs recombination mechanisms to synthesize across the lesion, Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission:	494nm/518nm
Properties:	Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target:	PCNA [Proliferation ] Conjugated
Short name:	FITC Conjugated, PCNA [Proliferation Marker] Antibody
Technique:	Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	FITC
Alternative name:	fluorecein coupled, PCNA [expantion detection labelled] (Antibody to)
Alternative technique:	antibodies
Identity:	8729
Gene:	PCNA | More about : PCNA
Long gene name:	proliferating cell nuclear antigen
Locus:	20p12, 3
Discovery year:	1990-01-15
GenBank acession:	J04718
Entrez gene record:	5111
Pubmed identfication:	2565339
Havana BLAST/BLAT:	OTTHUMG00000031798

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• #dna
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• #year