| Long name: |
FITC Conjugated, PAI-2/SerpinB2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PAI-2/SerpinB2 |
| Specificity: |
This is a highly specific antibody against PAI-2/SerpinB2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human PAI-2 |
| Gene ID number: |
5055 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
It was first discovered in the placenta, SerpinB2 also inhibits tissue plasminogen activator (t-PA), SerpinB2 is found in saliva, SerpinB2 is made by many cell types, SerpinB2 levels are elevated in serum during pregnancy, The shorter form has a deletion just after the start of the mature protein, The structure of PAI-2 is not terribly similar to PAI-1, although it was lowered in some cancers, and PAI-1 is much more efficient that SerpinB2 on both forms of plasminogen activator, and given the name PAI-2 because of the ability to inhibit urokinase plasminogen activator (u-PA) at low micromolar efficiency, and in leukemia, and in the skin, and is found intracellularly as an unglycosylated kDa protein, and secreted as a 60 kDa protein, breast cancer and ovarian cancer, but it is unclear what the relative production and distribution is for the shorter sequence, but with micromolar efficiency, has been reported, however, secreted by gingival fibroblasts, which is an E clade serpin, with a predicted mass of 43, 1 kDa and a pI of 5, 69, A shorter SerpinB2 isoform of 382 amino acids, SerpinB2 is a serine proteinase inhibitor of the ovalbumin like B clade of serpins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
HsT1201, Monocyte Arg serpin, Monocyte Arg-serpin, PAI, PAI 2, PAI-2, PAI2, PAI2A, PAI2_RAT, PLANH2, Placental plasminogen activator inhibitor, Plasminogen activator inhibitor 2, Plasminogen activator inhibitor 2 type A, Serpin peptidase inhibitor clade B ovalbumin member 2, SerpinB2, Serpinb2, Urokinase inhibitor, plasminogen activator inhibitor 2, Serpin B2 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PAI-2/SerpinB2 Conjugated |
| Short name: |
FITC Conjugated, PAI-2/SerpinB2 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
clade B (ovalbumin), fluorecein coupled, member 2 (Antibody to), PAI-2/serpin peptidase inhibitor |
| Alternative technique: |
antibodies |