| Long name: |
ALEXA FLUOR 594 Conjugated, PAI-2/SerpinB2 Polyclonal Antibody |
| Also known as: |
Anti-PAI-2/SerpinB2 PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PAI-2/SerpinB2 |
| Specificity: |
This is a highly specific antibody against PAI-2/SerpinB2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PAI-2 |
| Gene ID Number: |
5055 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
It was first discovered in the placenta, SerpinB2 also inhibits tissue plasminogen activator (t-PA), SerpinB2 is found in saliva, SerpinB2 is made by many cell types, SerpinB2 levels are elevated in serum during pregnancy, The shorter form has a deletion just after the start of the mature protein, The structure of PAI-2 is not terribly similar to PAI-1, although it was lowered in some cancers, and PAI-1 is much more efficient that SerpinB2 on both forms of plasminogen activator, and given the name PAI-2 because of the ability to inhibit urokinase plasminogen activator (u-PA) at low micromolar efficiency, and in leukemia, and in the skin, and is found intracellularly as an unglycosylated kDa protein, and secreted as a 60 kDa protein, breast cancer and ovarian cancer, but it is unclear what the relative production and distribution is for the shorter sequence, but with micromolar efficiency, has been reported, however, secreted by gingival fibroblasts, which is an E clade serpin, with a predicted mass of 43, 1 kDa and a pI of 5, 69, A shorter SerpinB2 isoform of 382 amino acids, SerpinB2 is a serine proteinase inhibitor of the ovalbumin like B clade of serpins |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
HsT1201, Monocyte Arg serpin, Monocyte Arg-serpin, PAI, PAI 2, PAI-2, PAI2, PAI2A, PAI2_RAT, PLANH2, Placental plasminogen activator inhibitor, Plasminogen activator inhibitor 2, Plasminogen activator inhibitor 2 type A, Serpin peptidase inhibitor clade B ovalbumin member 2, SerpinB2, Serpinb2, Urokinase inhibitor, plasminogen activator inhibitor 2, Serpin B2 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
PAI-2/SerpinB2 |
| Short name: |
PAI-2/SerpinB2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, clade B (ovalbumin), member 2 (Antibody to), PAI-2/serpin peptidase inhibitor |
| Alternative technique: |
antibodies |